Clinically proven to block heartburn for 24 hours.*1

With one Prilosec OTC pill a day, you can block frequent heartburn symptoms before they strike for a full 24 hours of heartburn relief. That way you can power on with your day—and rest at night—without concern that your frequent heartburn will flare up. That’s because Prilosec OTC fights heartburn day and night by shutting down many of the acid pumps in your stomach. It can be the all-day, all-night heartburn protection you need.*

Available in 14-, 28-, and 42-pill packages.

1Allgood LD et al. Comparison of Prilosec OTC (omeprazole magnesium 20.6 mg) to placebo for 14 days in the treatment of frequent heartburn. J Clin Pharm Ther 2005; 30 (2): 105-12

Ratings And Reviews

This area allows consumers like you to express their own opinions and comments. Prilosec OTC does not represent or warrant the accuracy of any statements or product claims made here, nor endorses any opinions expressed within this section.

No Star
Five Star
4.68/5 (385)
  • Value:
  • Quality:
97% Recommended

No Star
Five Star


great for heartburn and I recommend it. have been taken for years and seems to be the only over the counter medicine that works for me

Originally posted on US

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New York,NY
No Star
Five Star

great product

I love this product. I am a great fan of its effectiveness. I think there is no other product in the market that outperforms prilosec

Yes, I recommend this product!